One-pot synthesis of carbocyclic or heterocyclic compounds, especially pyrimidine useful as components of natural products or drugs, from acid halide, alkyne and active hydrogen compound
DE10320453A1
New Actinonin Bioisosteres
DE10316081A1
New compounds with antibacterial activity
DE10305531A1
New tubulysin compound conjugates with polymers or biomolecules, having reduced toxicity compared with parent tubulysin, especially useful for treating tumor diseases
DE10300049A1
New compounds that inhibit factor VIIa
DE10256976A1
Use of specific hydroxamic acids for inhibition of methionine aminopeptidase, useful for treatment of bacterial or fungal infections, or cancers and other diseases associated with angiogenesis
DE10252719A1
New tubulysin analogs, useful for treating tumor or cancer diseases, immunologically induced or autoimmune diseases, inflammatory diseases or rheumatoid arthritis or for surface modification of implants
DE10247233A1
New 4-substituted quinoline derivatives, useful for treating bacterial infections, optionally including additional ring nitrogens
DE10230872A1
Process for the preparation of substituted thiazol-2-ylmethyl esters
DE10230875A1
New tubulysin compound conjugates with polymers or biomolecules, having reduced toxicity compared with parent tubulysin, especially useful for treating tumor diseases
DE10230874A1
New tubulysin analogs, useful for treating tumor or cancer diseases, immunologically induced or autoimmune diseases, inflammatory diseases or rheumatoid arthritis or for surface modification of implants
DE10223908A1
Process for the preparation of substituted pyridines
